It’s no secret that John Mayer has a bit of a reputation for being a ladies’ man, but his latest conquest takes him into the realm of married women.

Rumor has it that the “Waiting on the World to Change” singer set his sights on Giada De Laurentiis, who is married to Anthropologie designer Todd Thompson and has a two-year-old daughter with him.

Earlier this week, the rumor mill was buzzing that Jennifer Aniston and John Mayer had rekindled the old flame, but come to find out, those reports were false.

Taking to his blog to set the record straight, the “Daughters” singer wrote, "This is equal parts fabricated, cobbled together and misleading.”

Having avoided another press-grabbing hook-up as of late, John Mayer definitely isn't going without his fair share of time with the ladies.

According to Life and Style insiders, the "Why Georgia?" crooner has been busily hitting up various New York City hotspots in hopes of landing a short-term romance.